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Viral Stock Production

High-Titer Virus Production and Reverse Genetics

Microbiologics are the world’s leading experts and go-to collaborators for growing, titering, and purifying viruses from a variety of species. We are classified to handle BSL-2 and BSL-3 pathogens in our certified biocontainment laboratories. We are skilled in making both wild type and recombinant viruses and can grow viruses from the 10 ml scale to the 16 liter scale.

Virus Products:

  • Crude infected cell extracts
  • Infectious virus preparations
  • Highly purified infectious virus preparations
  • Quantitated virus samples for use in device validation
  • Engineered virus containing your gene of interest
  • Quantitated viral proteins and nucleic acids
  • Viral RNA and DNA
  • Viral protein extracts
  • Inactivated virus

Customized viral stock production.

Growing, titering, and purifying viruses from a variety of species.

High-Titer Virus Production

Our highly specialized team has extensive knowledge and skill in making both wild type and recombinant viruses. Below are just a few examples of the viruses we have in our vast library of biomaterials. We can also help source additional virus species of interest if needed, or if you already have your own strain, we can help you securely send it to us.

  • Adenovirus
  • Influenza A & B
  • Herpes
  • Phage
  • Polio
  • Respiratory Syncytial Virus
  • Rhinovirus
  • SARS CoV-2
  • Varicella-Zoster Virus

Reverse Genetics

For drug discovery projects where mutations in viral polymerases or other viral genes are required for study, Microbiologics offers reverse genetics services. Using molecular biology techniques, reverse genetics enables production of viruses with intentional changes to existing genes, such as desired mutations. It also enables deletion of all or part of a viral gene, or addition of genes not normally found in the viruses. For example, a BSL-2 virus can be engineered to express glycoproteins from other viruses, including BSL-3 and BSL-4 viruses. Our team has experience developing reverse genetics systems for Influenza A and B, Vesicular stomatitis virus (VSV) and SARS-CoV-2.

Connect with the Viral Stock Production Team

We’re ready to answer your questions.

Viral Stock Production Contact:

Business Development
Phone: +1.800.599.2847
Email: businessdevelopment@microbiologics.com

We are the world’s leading experts and go-to collaborators for biological products and services.

Learn more about our capabilities and areas of expertise at each of our locations.