CUSTOM AND OFF THE SHELF VIRUS STOCKS

For Research, Antiviral Screening, Validation Studies, Limit of Detection, Assay Development and Beyond

Virus stocks play a critical role in the development of antiviral drugs, vaccines, biopharmaceuticals and diagnostic technologies that help combat viral threats and protect public health globally. Virologists rely on well characterized, highly purified virus stocks to ensure the validity and integrity of their drug screening, efficacy testing, mechanism of action studies, assay development and more. As pioneers in infectious disease materials and assay services, Microbiologics remains the industry’s trusted source for custom and off-the-shelf virus stock production.

From the household names like Influenza to emerging threats like Dengue, we work with a broad portfolio of infectious agents. We are known for our expertise in both cell-based and egg-based propagation of viruses. Additionally, we offer reverse genetics services, enabling intentional modifications to existing genes or the introduction of new genes not typically found in the viruses.

Whether you're seeking off-the-shelf or made-to-order materials, Microbiologics is your trusted partner for virus stocks. Our offerings include:

• Crude and purified virus
• Infectious and inactivated virus
• High titer virus
• ddPCR quantification
• Sequencing
• Virus models to support adventitious virus screening
• Recombinant virus
• Virus banking
• Cell banking
• Viral RNA and DNA

CUSTOM VIRUS STOCKS

We offer the most extensive customization options for virus production, ensuring our partners receive a final product that meets their specific needs. Our team of approachable experts will work with you, providing guidance where and when you need it throughout each project. With state-of-the-art facilities, advanced technologies and a highly skilled team, we can customize virtually any aspect of the virus stock production process from choice of host cells and culture conditions to purification, titration, inactivation or attenuation.

All our virus stocks are produced at Microbiologics' Global Virology Center in San Diego which encompasses multiple BSL-2 and BSL-3 laboratories. This facility operates under a Quality Management System that has received ISO 13485 certification. Below are just a few examples of the viruses we have in our vast library of viruses. We can also source additional virus species of interest if needed, or if you already have your own strain, we can further support your research needs.

*multiple strains available

HIGH-TITER OFF-THE-SHELF (OTS) VIRUS STOCKS

Microbiologics off-the-shelf virus stocks provide convenience and reliability. With our extensive selection readily available for immediate shipment, you have swift access to the strains you need to keep your projects moving forward. Our virus stocks boast the highest titers and copy numbers in the industry, ensuring optimal performance in your research or diagnostic applications. Confidently advance your work with Microbiologics' off-the-shelf virus stocks at your fingertips.

COMMONLY REQUESTED VIRUS STRAINS AVAILABLE OFF-THE-SHELF

*Multiple strains are available. Submit a contact form below to request details.

PURIFIED VIRAL STOCK FOR ADVENTITIOUS AGENT DETECTION

Biopharmaceutical manufacturers rely on adventitious virus testing to ensure products are free of contaminants that could harm patients or compromise quality. We are proud to be the industry’s leading experts and go-to collaborators for the broadest portfolio of off-the-shelf and custom virus stock solutions to support Viral Safety and Viral Clearence testing. Whether you're seeking ready-to-use solutions or tailored formulations, Microbiologics is your trusted partner in safeguarding the integrity of your biopharmaceutical products.

Looking for readily available purified stock or custom product? Check out our Viral Safety Solutions for more information on Viral Stock and NGS sequencing.

RECOMBINANT VIRUS

We specialize in generating recombinant virus stocks to advance the research and development of antiviral drugs, therapeutics, and vaccines. Applications for recombinant virus include the generation of vaccine candidates, rapid vaccine development, high-throughput screening for vaccine efficacy, and assay development including virus neutralization, antiviral screening and pathogenicity studies. Our reverse genetics methods allow for precise modifications, such as desired mutations or deletions/additions of viral genes. For example, a BSL-2 virus can be engineered to express glycoproteins from other viruses, including BSL-3 viruses. We have expertise in designing reverse genetics systems for Influenza A and B and more. If you are unsure which viral system is right for your research, our skilled virologists are happy to provide guidance and recommendations.

WHY PARTNER WITH MICROBIOLOGICS

Extensive Portfolio: We are proud to be the industry’s trusted source for live, inactivated, and recombinant viruses. Our diverse portfolio encompasses hundreds of fully characterized viral strains. We offer the highest titer and copy number viral stock materials in the industry, making them ideal for a wide range of applications, spiking into matrixes, or creating different dilutions as needed.

Unparalleled Customization: Whether you’re using cell-based assays, PCR, NGS, ELISA, in-vivo models or other methodologies, we offer extensive customization options, helping our clients design viral stocks to meet their exact requirements. Examples include purified material, single-use aliquots, multi-target stocks, and pre-spiking into your own cell-line. Our team is also skilled at applying reverse genetics methods to design and produce recombinant viruses.

Scalable Supply: Whether you need large quantities for high-throughput screening and assay development, or smaller volumes for validation and LOD studies, we've got you covered. With our scalable capabilities, we can accommodate orders of any size, ensuring you have a steady and reliable source of viral material to support your ongoing activities.

Stringent Quality Assurance: Quality is at the core of everything we do. All our virus stocks undergo rigorous testing procedures to ensure the highest standards of quality and reliability. From initial culturing to final distribution, every step of the production process is meticulously monitored and evaluated to guarantee consistency and performance.

Approachable Experts: Partnering with Microbiologics means gaining access to a team of friendly and trusted experts who are committed to supporting their fellow scientists with virology superior products and services, unmatched customization options, and exceptional customer experiences. We would love to collaborate and advance science for a safer, healthier world together.